Mycophenolate mofetil in nonlupus glomerulonephropathy Academic Article Article uri icon

Overview

MeSH Major

  • Genetic Testing
  • High-Throughput Nucleotide Sequencing
  • Polycystic Kidney, Autosomal Dominant

abstract

  • Mycophenolate mofetil (MMF) initially found widespread use in the immunoprophylaxis of rejection in organ transplantation. It has subsequently been used in lupus glomerulonephritis, where early studies have shown it to be effective in induction and maintenance therapy. The randomized studies have mostly studied small groups of patients and their conclusions do need to be confirmed in larger studies. MMF has also been used in small numbers of patients in a variety of nonlupus glomerulopathies, which have different underlying immunopathology as well as clinical course, including IgA nephropathy, membranous nephropathy, focal segmental glomerulosclerosis, membranoproliferative glomerulonephritis, hepatitis-C-associated glomerulonephritis and even Goodpasture's syndrome. In this article, we discuss its use in such nonlupus glomerular diseases. © 2005 Edward Arnold (Publishers) Ltd.

publication date

  • April 18, 2005

Research

keywords

  • Academic Article

Identity

PubMed ID

  • 15803930

Additional Document Info

volume

  • 14

number

  • SUPPL. 1