Two birds with one stone--dealing with nuclear transport and spindle assembly. uri icon

Overview

abstract

  • Spindle assembly and nuclear transport both utilize the same simple device: Ran-GTP-sensitive interaction of importin beta and its cargo proteins. In this issue of Cell, report that one of these cargos required for spindle assembly turns out to be Rae1, previously known as an mRNA export protein. This study reveals the importance of RNAs in spindle structure.

publication date

  • April 22, 2005

Research

keywords

  • Active Transport, Cell Nucleus
  • Spindle Apparatus

Identity

Scopus Document Identifier

  • 17444385251

Digital Object Identifier (DOI)

  • 10.1016/j.cell.2005.04.003

PubMed ID

  • 15851021

Additional Document Info

volume

  • 121

issue

  • 2