Methodology for biologically-based treatment planning for combined low-dose-rate (permanent implant) and high-dose-rate (fractionated) treatment of prostate cancer Academic Article uri icon

Overview

MeSH Major

  • Algorithms
  • Brachytherapy
  • Prostatic Neoplasms
  • Radiotherapy, Conformal

abstract

  • We describe new methodology for biologically based treatment planning for patients who receive combined low-dose-rate brachytherapy and external beam radiotherapy for prostate cancer. Using relevant mathematical tools, we demonstrate the feasibility of fusing dose distributions from each treatment for this combined regimen, which can then be expressed as isoeffective dose distributions. Based on this information, dose constraints for the rectum and urethra are described which could be used for planning such combination regimens.

publication date

  • March 2005

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.ijrobp.2004.06.251

PubMed ID

  • 15708248

Additional Document Info

start page

  • 702

end page

  • 13

volume

  • 61

number

  • 3