A DNA transcription code for cell-specific gene activation by Notch signaling
Academic Article
Overview
MeSH Major
DNA
DNA-Binding Proteins
Drosophila
Gene Expression Regulation
Membrane Proteins
Signal Transduction
abstract
The SPS architecture functions to mediate or enable the Notch-proneural transcriptional synergy which drives Notch target gene activation in specific cells. Thus, SPS+A is an architectural DNA transcription code that programs a cell-specific pattern of gene expression.
