Pitavastatin Downregulates Expression of the Macrophage Type B Scavenger Receptor, CD36
Academic Article
Overview
MeSH Major
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Macrophages
Quinolines
abstract
The present data demonstrate that pitavastatin prevents OxLDL uptake by macrophages through PPARgamma-dependent inhibition of CD36 expression and suggest that pitavastatin could modulate CD36-mediated atherosclerotic foam cell formation.