Impact of a hospital-based antimicrobial management program on clinical and economic outcomes. Academic Article uri icon

Overview

abstract

  • Inappropriate use of antimicrobial agents results in unnecessary exposure to medication, persistent or progressive infection, emergence of resistance, and increased costs. We implemented a program to control use of restricted agents while improving care. This study compared 2 major mechanisms for improving use of antimicrobial agents: (1) recommendations made by the Antimicrobial Management Team (AMT), which included a clinical pharmacist backed up by a physician from the Division of Infectious Diseases (ID), and (2) recommendations made by ID fellows. Outcome measures included appropriateness of recommendations, cure rate, number of treatment failures, and cost of care, which were assessed for 180 patients. The AMT outperformed the ID fellows in all outcomes examined by the study (including appropriateness [87% vs. 47%; P<.001], cure rate [64% vs. 42%; P=.007], and treatment failures [15% vs. 28%; P=.03]), although the differences in economic outcomes between cases managed by the AMT and those managed by the ID fellows were not statistically significant. In an academic setting with a restricted formulary, the AMT demonstrated better antimicrobial prescribing than ID fellows.

publication date

  • July 5, 2001

Research

keywords

  • Anti-Bacterial Agents
  • Communicable Diseases
  • Hospitals
  • Infection Control
  • Outcome and Process Assessment, Health Care

Identity

Scopus Document Identifier

  • 0034922947

PubMed ID

  • 11438891

Additional Document Info

volume

  • 33

issue

  • 3