Phase I study of green tea extract in patients with advanced lung cancer
Carcinoma, Non-Small-Cell Lung
Carcinoma, Small Cell
This study suggests that while relatively nontoxic at a dose of 3 g/m2 per day, GTE likely has limited activity as a cytotoxic agent, and further study of GTE as a single-agent in established malignancies may not be warranted. Further studies should focus on the potential chemopreventive and chemotherapy-enhancing properties of GTE.