Cross-species comparisons of cancer signaling Comment uri icon

Overview

MeSH Major

  • Neoplasms
  • Signal Transduction

abstract

  • Modeling of human cancer in genetically engineered mice and genome-wide measurements of mRNA expression have now been combined to accelerate the search for new molecularly targeted therapies against cancer. Looking forward, we propose a community-wide systematic effort to model and characterize an array of different cancer-related aberrant signaling pathways in several mouse models of cancer.

publication date

  • January 2005

Research

keywords

  • Comment

Identity

Digital Object Identifier (DOI)

  • 10.1038/ng0105-7

PubMed ID

  • 15624012

Additional Document Info

start page

  • 7

end page

  • 8

volume

  • 37

number

  • 1