Association of leptin levels with obesity and blood pressure: Possible common genetic variation Academic Article uri icon

Overview

MeSH Major

  • Blood Pressure
  • Leptin
  • Obesity
  • Quantitative Trait, Heritable

abstract

  • BP and OB covariation is substantially mediated by circulating leptin levels. As a result, body fat has only a weak independent effect on BP variation after adjustment for leptin levels. Our findings also strongly suggest that genetic variation in body mass index, SKFs, and even body CRCs, as well as of SBP is due to genetic variation of leptin. Genetic variation of diastolic blood pressure in the present sample, however, shared very little with that of leptin.

publication date

  • January 2005

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1038/sj.ijo.0802826

PubMed ID

  • 15505633

Additional Document Info

start page

  • 85

end page

  • 92

volume

  • 29

number

  • 1