Are pANCA, ASCA, or Cytokine Gene Polymorphisms Associated with Pouchitis? Long-term Follow-up in 102 Ulcerative Colitis Patients Academic Article uri icon

Overview

MeSH Major

  • Antibodies
  • Antibodies, Antineutrophil Cytoplasmic
  • Colitis, Ulcerative
  • Cytokines
  • Polymorphism, Genetic
  • Postoperative Complications
  • Pouchitis

abstract

  • Perinuclear antineutrophil cytoplasmic antibodies and anti-saccharomyces cerevesiae antibodies are not correlated with pouchitis, but interleukin-1 receptor antagonist and TNF may play a role in its development. Further evaluation of these markers in pouchitis will require larger populations, long-term prospective observation, and studies that correlate polymorphisms with specific immunologic functions.

publication date

  • March 2004

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1111/j.1572-0241.2004.04107.x

PubMed ID

  • 15056081

Additional Document Info

start page

  • 432

end page

  • 41

volume

  • 99

number

  • 3