Coexpression of herpesviral thymidine kinase reporter gene and VEGF gene for noninvasive monitoring of therapeutic gene transfer: An in vitro evaluation Academic Article uri icon

Overview

MeSH Major

  • Gene Transfer Techniques
  • Genetic Therapy
  • Muscle Cells
  • Thymidine Kinase
  • Vascular Endothelial Growth Factor A
  • Viral Proteins

abstract

  • The usefulness of a vector coexpressing HSV1-tk and VEGF for noninvasive imaging of expression of a therapeutic transgene has been demonstrated in vitro. This approach may allow for future in vivo monitoring of cardiac angiogenesis gene therapy.

publication date

  • October 2004

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 15471843

Additional Document Info

start page

  • 1743

end page

  • 6

volume

  • 45

number

  • 10