The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO Academic Article uri icon

Overview

MeSH Major

  • Carrier Proteins
  • Crohn Disease
  • Intracellular Signaling Peptides and Proteins
  • Protein-Serine-Threonine Kinases
  • Signal Transduction
  • Ubiquitin

abstract

  • These data suggest that this novel mode of regulation of the NF-kB signaling pathway could be a factor underlying the pathogenesis of Crohn's disease.

publication date

  • December 29, 2004

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.cub.2004.12.032

PubMed ID

  • 15620648

Additional Document Info

start page

  • 2217

end page

  • 27

volume

  • 14

number

  • 24