Inflammatory disease in older adults: Cranial arteritis Review uri icon

Overview

MeSH Major

  • Giant Cell Arteritis

abstract

  • Cranial arteritis (CA), also called giant cell arteritis or temporal arteritis, is a vasculitis primarily affecting adults over age 50. It is a large vessel vasculitis, and giant cells classically can be identified on histopathologic examination of temporal arteries, but are not essential for diagnosis. Patients typically present with severe headaches, fatigue, polymyalgia-like symptoms, or ischemic complaints such as jaw claudication. Visual loss is the major feared irreversible outcome and can occur in up to 50% of those with untreated disease. Glucocorticoids, typically high dose prednisone (> or = 60 mg/d) is the first-line treatment and successfully controls the inflammatory disease in the vast majority of patients. Most patients can be tapered off steroids within 6 months to 2 years.

publication date

  • December 2004

Research

keywords

  • Review

Identity

Language

  • eng

PubMed ID

  • 15667019

Additional Document Info

start page

  • 25

end page

  • 9; quiz 30

volume

  • 59

number

  • 12