Appropriateness of breast-conserving treatment of breast carcinoma in women with germline mutations in BRCA1 or BRCA2: A clinic-based series Academic Article uri icon

Overview

MeSH Major

  • Breast Neoplasms
  • Carcinoma
  • Genes, BRCA1
  • Genes, BRCA2
  • Germ-Line Mutation
  • Mastectomy, Segmental

abstract

  • Women with BRCA-associated breast carcinoma who undergo BCT appear to have risks of MIBC that are similar to those reported for young women without known mutations. The indications for unilateral mastectomy in this group of women should be the same as those for women with nonhereditary carcinoma. However, significant risks of CBC and possibly late MIBC may prompt the serious consideration of bilateral mastectomy as a preventive measure.

publication date

  • January 2005

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1002/cncr.20728

PubMed ID

  • 15558796

Additional Document Info

start page

  • 44

end page

  • 51

volume

  • 103

number

  • 1