Heritability of left ventricular dimensions and mass in American Indians: The Strong Heart Study
Diabetes Mellitus, Type 2
Hypertrophy, Left Ventricular
A substantial proportion of the variance of left ventricular dimensions and mass can be explained by heredity, independent of the effects of sex, age, body size, blood pressure, heart rate, medications and diabetes. Identification of genes influencing left ventricular size and geometry may provide mechanistic and therapeutic targets to prevent left ventricular hypertrophy.