Consistent Antibody Response against Ganglioside GD2 Induced in Patients with Melanoma by a GD2 Lactone-Keyhole Limpet Hemocyanin Conjugate Vaccine plus Immunological Adjuvant QS-21 Academic Article uri icon

Overview

MeSH Major

  • Adjuvants, Immunologic
  • Cancer Vaccines
  • Gangliosides
  • Hemocyanin
  • Melanoma
  • Vaccines, Conjugate

abstract

  • GD2L-KLH conjugate vaccine plus adjuvant QS-21 induces antibodies against GD2 that bind to the cell surface and induce complement-dependent cytotoxicity in the majority of patients with melanoma.

publication date

  • November 2003

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 14614001

Additional Document Info

start page

  • 5214

end page

  • 20

volume

  • 9

number

  • 14