Adenoviral-mediated transfer of vascular endothelial growth factor 121 cDNA enhances myocardial perfusion and exercise performance in the nonischemic state Academic Article uri icon

Overview

MeSH Major

  • Adenoviridae
  • DNA, Complementary
  • Exercise Tolerance
  • Gene Transfer Techniques
  • Genetic Therapy
  • Myocardial Ischemia
  • Myocardial Reperfusion
  • Vascular Endothelial Growth Factor A

abstract

  • Adenovirus encoding-mediated transfer of vascular endothelial growth factor 121 induces an enhancement in regional perfusion in nonischemic myocardium that corresponds to changes in exercise tolerance. Adenovirus-encoding vascular endothelial growth factor therapy may be useful for inducing angiogenesis in the nonischemic state, such as for prophylactic therapy of early coronary artery disease.

publication date

  • February 2004

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.jtcvs.2003.06.015

PubMed ID

  • 14762365

Additional Document Info

start page

  • 535

end page

  • 40

volume

  • 127

number

  • 2