Functional interplay between the macrophage scavenger receptor class B type I and pitavastatin (NK-104) Academic Article uri icon

Overview

MeSH Major

  • Anti-Inflammatory Agents, Non-Steroidal
  • Gene Expression Regulation
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Macrophages
  • Membrane Proteins
  • Quinolines
  • Receptors, Immunologic
  • Receptors, Lipoprotein

abstract

  • Our data demonstrate that pitavastatin can stimulate macrophage SR-BI expression by reduction of cholesterol biosynthetic intermediates and antiinflammatory action and suggest additional pleiotropic effects of statins by which they may reduce the incidence of coronary heart disease.

publication date

  • November 30, 2004

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1161/01.CIR.0000148368.79202.F1

PubMed ID

  • 15557368

Additional Document Info

start page

  • 3472

end page

  • 9

volume

  • 110

number

  • 22