Radioimmunotherapy of Prostate Cancer in Human Xenografts Using Monoclonal Antibodies Specific to Prostate Specific Membrane Antigen (PSMA): Studies in Nude Mice Academic Article uri icon

Overview

MeSH Major

  • Antigens, Surface
  • Glutamate Carboxypeptidase II
  • Prostatic Neoplasms
  • Radioimmunotherapy

abstract

  • In nude mice bearing PSMA positive tumors, radiation dose to the tumor with (90)Y-DOTA-J591 is greater for large tumors than with (131)I-J591. The theoretical and practical considerations strongly suggest that (90)Y-DOTA-huJ591 may be a suitable radiopharmaceutical for the treatment of prostate cancer.

publication date

  • February 2004

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1002/pros.10281

PubMed ID

  • 14716739

Additional Document Info

start page

  • 145

end page

  • 55

volume

  • 58

number

  • 2