Fallopian tube and primary peritoneal carcinomas associated with BRCA mutations Review uri icon

Overview

MeSH Major

  • Fallopian Tube Neoplasms
  • Genes, BRCA1
  • Germ-Line Mutation
  • Jews
  • Peritoneal Neoplasms

abstract

  • Substantial proportions of Ashkenazi Jewish patients with FTC or PPC are BRCA mutation carriers. Patients with BRCA-associated FTC or PPC are younger at diagnosis and have improved survival compared with patients without a BRCA mutation. Although the lifetime risks of FTC or PPC for patients with BRCA heterozygotes are greater than those for the general population, the absolute risks seem relatively low.

publication date

  • November 15, 2003

Research

keywords

  • Review

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1200/JCO.2003.04.131

PubMed ID

  • 14615451

Additional Document Info

start page

  • 4222

end page

  • 7

volume

  • 21

number

  • 22