Fully synthetic carbohydrate-based vaccines in biochemically relapsed prostate cancer: Clinical trial results with α-N-acetylgalactosamine-O- serine/threonine conjugate vaccine Academic Article uri icon

Overview

MeSH Major

  • Antigens, Tumor-Associated, Carbohydrate
  • Cancer Vaccines
  • Neoplasm Recurrence, Local
  • Prostatic Neoplasms
  • Vaccines, Conjugate

abstract

  • A safe synthetic conjugate vaccine in a trimer formation was developed that can break immunologic tolerance by inducing specific humoral responses. It seemed to affect the biochemical progression of the disease as determined by a change in PSA log slope.

publication date

  • December 2003

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1200/JCO.2003.04.112

PubMed ID

  • 14645418

Additional Document Info

start page

  • 4292

end page

  • 8

volume

  • 21

number

  • 23