Greater availability of brain dopamine transporters in major depression shown by [99mTc]TRODAT-1 SPECT imaging Academic Article uri icon

Overview

MeSH Major

  • Brain
  • Depressive Disorder, Major
  • Membrane Glycoproteins
  • Membrane Transport Proteins
  • Organotechnetium Compounds
  • Tomography, Emission-Computed, Single-Photon
  • Tropanes

abstract

  • Dopamine transporter affinity may be higher than normal in the basal ganglia of depressed patients. These findings suggest that dopamine function may be altered in depression and may also be a mechanism of antidepressant activity.

publication date

  • October 2003

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1176/appi.ajp.160.10.1836

PubMed ID

  • 14514499

Additional Document Info

start page

  • 1836

end page

  • 41

volume

  • 160

number

  • 10