Transcriptome analysis of the response of Pseudomonas aeruginosa to hydrogen peroxide. Academic Article uri icon

Overview

MeSH

  • Gene Expression Profiling
  • Oxidative Stress
  • RNA, Messenger

MeSH Major

  • Bacterial Proteins
  • Gene Expression Regulation, Bacterial
  • Genome, Bacterial
  • Hydrogen Peroxide
  • Oxidants
  • Pseudomonas aeruginosa
  • Transcription, Genetic

abstract

  • Pseudomonas aeruginosa must often overcome a high concentration of oxidants to successfully infect the human host. We report here the results of a transcriptome profiling comparing cells treated with H(2)O(2) and untreated controls. The data indicate that the early response of P. aeruginosa to H(2)O(2) consists of an upregulation of protective mechanisms and a downregulation of primary metabolism.

publication date

  • January 2004

has subject area

  • Bacterial Proteins
  • Gene Expression Profiling
  • Gene Expression Regulation, Bacterial
  • Genome, Bacterial
  • Hydrogen Peroxide
  • Oxidants
  • Oxidative Stress
  • Pseudomonas aeruginosa
  • RNA, Messenger
  • Transcription, Genetic

Research

keywords

  • Journal Article

Identity

Language

  • eng

PubMed Central ID

  • PMC303446

PubMed ID

  • 14679246

Additional Document Info

start page

  • 248

end page

  • 252

volume

  • 186

number

  • 1