Transcriptome analysis of the response of Pseudomonas aeruginosa to hydrogen peroxide.
Gene Expression Profiling
Gene Expression Regulation, Bacterial
Pseudomonas aeruginosa must often overcome a high concentration of oxidants to successfully infect the human host. We report here the results of a transcriptome profiling comparing cells treated with H(2)O(2) and untreated controls. The data indicate that the early response of P. aeruginosa to H(2)O(2) consists of an upregulation of protective mechanisms and a downregulation of primary metabolism.