Management of recurrence and follow-up strategies for patients with seminoma and selected high-risk groups Article Report uri icon


MeSH Major

  • Sarcoidosis
  • Seminoma
  • Testicular Neoplasms


  • Seminoma is characterized by high sensitivity to both radiation and chemotherapy. Localized recurrences in the retroperitoneum after surveillance for stage I can be treated with radiotherapy; however, multiple or large bulky retroperitoneal recurrences or systemic metastasis requires cisplatin-based chemotherapy. Salvage chemotherapy for those who recur after initial CR to induction chemotherapy is based on ifosfamide- and cisplatin-containing regimens. Incomplete response or failure after induction chemotherapy requires high-dose chemotherapy and stem cell rescue. Patients with seminoma need long-term follow-up because of the possibility of late recurrence and the risk of a second primary tumor.

publication date

  • November 2003



  • Report


Digital Object Identifier (DOI)

  • 10.1016/S0094-0143(03)00063-6

PubMed ID

  • 14680316

Additional Document Info

start page

  • 803

end page

  • 17


  • 30


  • 4