Asymmetric dimethylarginine (ADMA): A novel risk factor for endothelial dysfunction: Its role in hypercholesterolemia Academic Article uri icon

Overview

MeSH Major

  • Arginine
  • Endothelium, Vascular
  • Hypercholesterolemia

abstract

  • We find that ADMA is elevated in young HC individuals. Elevation of ADMA is associated with impaired endothelium-dependent vasodilation and reduced urinary nitrate excretion. This abnormality is reversed by administration of L-arginine. ADMA may be a novel risk factor for endothelial dysfunction in humans.

publication date

  • November 3, 1998

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 9799202

Additional Document Info

start page

  • 1842

end page

  • 7

volume

  • 98

number

  • 18