Differential Amplification and Overexpression of HER-2/neu, p53, MIB1, and Estrogen Receptor/Progesterone Receptor among Medullary Carcinoma, Atypical Medullary Carcinoma, and High-Grade Invasive Ductal Carcinoma of Breast Academic Article uri icon

Overview

MeSH Major

  • Breast Neoplasms
  • Carcinoma, Ductal, Breast
  • Carcinoma, Medullary
  • Ki-67 Antigen
  • Receptor, ErbB-2
  • Receptors, Estrogen
  • Receptors, Progesterone
  • Tumor Suppressor Protein p53

abstract

  • Medullary carcinoma of breast is distinct from AMC and HGIDC with prominent lymphocytic infiltrates in amplification and overexpression of HER-2/neu. This difference may account for its different clinical and biological behavior, and may potentially aid in diagnosis and management of these groups of patients.

publication date

  • November 2003

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 14567723

Additional Document Info

start page

  • 1458

end page

  • 64

volume

  • 127

number

  • 11