Detection of HER-2/neu gene amplification in breast cancer using a novel polymerase chain reaction/ligase detection reaction technique Academic Article Article uri icon

Overview

MeSH Major

  • Antineoplastic Combined Chemotherapy Protocols
  • Colorectal Neoplasms
  • Consensus
  • Hyperthermia, Induced
  • Peritoneal Neoplasms
  • Practice Guidelines as Topic

abstract

  • The PCR/LDR technique successfully detects HER-2/neu gene amplification in clinical breast cancer specimens and shows 100% concordance with FISH. This technique is an accurate and rapid alternative to FISH with the potential for automation and high throughput analysis of HER-2/neu status in breast cancer.

publication date

  • September 2003

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1016/S1072-7515(03)00431-9

PubMed ID

  • 12946797

Additional Document Info

start page

  • 419

end page

  • 25

volume

  • 197

number

  • 3