Does the form of akinetic mutism linked to mesodiencephalic injuries bridge the double dissociation of Parkinson's disease and catatonia? Comment uri icon

Overview

MeSH Major

  • Brain
  • Cognition
  • Magnetic Resonance Imaging
  • Persistent Vegetative State

abstract

  • Northoff provides a compelling argument supporting a kind of "double dissociation" of Parkinson's disease and catatonia. We discuss a related form of akinetic mutism linked to mesodiencephalic injuries and suggest an alternative to the proposed "horizontal" versus "vertical" modulation distinction. Rather than a "directional" difference in patterned neuronal activity, we propose that both disorders reflect hypersynchrony within typically interdependent but segregated networks facilitated by a common thalamic gating mechanism.

publication date

  • October 2002

Research

keywords

  • Comment

Additional Document Info

start page

  • 586

end page

  • 587

volume

  • 25

number

  • 5