The central role of dendritic cells and interferon-α in SLE Article Report uri icon

Overview

MeSH Major

  • Autoimmune Diseases
  • Genes, Immunoglobulin
  • Immunoglobulin Variable Region

abstract

  • The disease model that the authors propose places interferon-alpha at the center of the immunologic abnormalities observed in systemic lupus erythematosus, and poses interferon-alpha and/or interferon-alpha-producing cells as novel targets for therapy in this disease. The authors surmise that type I interferon antagonists will bring systemic lupus erythematosus patients the relief that tumor necrosis factor antagonists brought to patients with rheumatoid arthritis.

publication date

  • September 2003

Research

keywords

  • Report

Identity

Digital Object Identifier (DOI)

  • 10.1097/00002281-200309000-00005

PubMed ID

  • 12960479

Additional Document Info

start page

  • 548

end page

  • 56

volume

  • 15

number

  • 5