Underpowering in randomized trials reporting a sample size calculation Academic Article Article uri icon

Overview

MeSH Major

  • Prostatic Neoplasms
  • Randomized Controlled Trials as Topic

abstract

  • Trials reporting sample size calculations for continuous endpoints published in the most reputable medical journals are often underpowered. There seems to be insufficient understanding that the SD of a sample of patients is a random variable, associated with imprecision, that cannot easily be extrapolated from one population to another.

publication date

  • August 2003

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1016/S0895-4356(03)00141-0

PubMed ID

  • 12954462

Additional Document Info

start page

  • 717

end page

  • 20

volume

  • 56

number

  • 8