Use of C4d as a diagnostic adjunct in lung allograft biopsies Academic Article Article uri icon

Overview

MeSH Major

  • Lymphoma, T-Cell, Cutaneous
  • Precancerous Conditions
  • Skin Neoplasms

abstract

  • In the context of acute rejection, C4d deposition correlates with clinical evidence of rejection and the degree of humoral rejection assessed pathologically; there is no association with the presence of histocompatibility related antibodies. It is a more specific predictor of allograft status compared to other immunoreactants. C4d deposition within the bronchial wall is a feature of BOS and hence may be used as a marker of chronic graft dysfunction. The antigenic target resulting in C4d deposition may not be histocompatibility related.

publication date

  • September 2003

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1034/j.1600-6143.2003.00152.x

PubMed ID

  • 12919095

Additional Document Info

start page

  • 1143

end page

  • 54

volume

  • 3

number

  • 9