Eicosapentaenoic acid restores tamoxifen sensitivity in breast cancer cells with high Akt activity Academic Article uri icon

Overview

MeSH Major

  • Breast Neoplasms
  • Estrogen Antagonists
  • Fatty Acids, Unsaturated
  • Gene Expression Regulation, Neoplastic
  • Phosphatidylinositol 3-Kinases
  • Protein-Serine-Threonine Kinases
  • Tamoxifen

abstract

  • These findings suggest that EPA may be useful for the treatment of tamoxifen-resistant breast cancer cells with high levels of activated Akt and provide the rationale to test this hypothesis in the clinic.

publication date

  • July 2003

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1093/annonc/mdg291

PubMed ID

  • 12853346

Additional Document Info

start page

  • 1051

end page

  • 6

volume

  • 14

number

  • 7