Automated, multiplex assay for high-frequency microsatellite instability in colorectal cancer Academic Article uri icon

Overview

MeSH Major

  • Adenocarcinoma
  • Chromosome Aberrations
  • Colorectal Neoplasms
  • DNA Mutational Analysis
  • Microsatellite Repeats

abstract

  • The multiplex assay identifies colon cancers with MSI-H by assessing three highly accurate microsatellite markers. This assay identifies a smaller MSI-H cohort with more homogeneous clinical features and is superior as a marker of favorable prognosis. It merits prospective evaluation as a marker of prognosis and as a screening test for HNPCC.

publication date

  • August 15, 2003

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1200/JCO.2003.11.133

PubMed ID

  • 12915601

Additional Document Info

start page

  • 3105

end page

  • 12

volume

  • 21

number

  • 16