Seeking the solution to the problem of metastatic renal carcinoma Editorial Article uri icon


MeSH Major

  • Kidney Neoplasms


  • It is estimated there will be 31,900 new cases and 11,900 deaths from renal carcinoma in the U.S. in 2003. Since 1950 there has been a 126% increase report in the incidence of renal carcinoma and a 36.5% increase in annual mortality. In the last 20 years, our understanding of tumors arising from the renal cortex has dramatically expanded because of advances in cytogenetics and histopathologic reclassification, improved abdominal imaging technology leading to a tumor stage migration, and changing surgical strategies. Despite these advances, our efforts to treat metastatic renal carcinoma either with systemic therapies or surgical intervention have been frustrated. In the article by Pantuck et al. in the issue of Cancer, the authors identify the adverse prognostic impact of metastatic regional lymph nodes in patients with metastatic disease when compared with patients with metastatic disease alone.

publication date

  • June 15, 2003



  • Editorial


Digital Object Identifier (DOI)

  • 10.1002/cncr.11439

PubMed ID

  • 12784326

Additional Document Info

start page

  • 2941

end page

  • 4


  • 97


  • 12