10-Propargyl-10-deazaaminopterin: An antifolate with activity in patients with previously treated non-small cell lung cancer Academic Article uri icon

Overview

MeSH Major

  • Aminopterin
  • Carcinoma, Non-Small-Cell Lung
  • Folic Acid Antagonists
  • Lung Neoplasms
  • Membrane Transport Proteins

abstract

  • The broad applicability of this new antifolate with limited toxicity and proven efficacy in NSCLC encourage further development of this compound. Several trials are now underway combining PDX with other chemotherapeutic agents and testing its efficacy in other cancers.

publication date

  • June 2003

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 12796370

Additional Document Info

start page

  • 2072

end page

  • 8

volume

  • 9

number

  • 6