Adjuvant Hepatic Arterial Chemotherapy Following Metastasectomy in Patients with Isolated Liver Metastases Article Conference Paper uri icon

Overview

MeSH Major

  • Dinoprostone
  • Endotoxins
  • Mitogen-Activated Protein Kinases
  • NF-kappa B
  • Prostaglandin-Endoperoxide Synthases
  • Wounds and Injuries

abstract

  • Biliary toxicity is an important potential side effect of hepatic arterial chemotherapy. Although larger randomized studies and this one suggest significant improvements in hepatic recurrences, these have not reliably translated into overall survival benefit. This fact, in light of the potential toxicity, would argue for a larger confirmatory trial of HAI in the adjuvant setting, incorporating recent advances in systemic therapy and careful attention to hepatotoxicity.

publication date

  • June 2003

Research

keywords

  • Conference Paper

Identity

Digital Object Identifier (DOI)

  • 10.1097/00000658-200306000-00006

PubMed ID

  • 12796574

Additional Document Info

start page

  • 782

end page

  • 8; discussion 788-9

volume

  • 237

number

  • 6