Treatment of former smokers with 9-cis-retinoic acid reverse loss of retinoic acid receptor-β expression in the bronchial epithelium: Results from a randomized placebo-controlled trial
Academic Article
Overview
MeSH Major
Antineoplastic Agents
Bronchi
Precancerous Conditions
Receptors, Retinoic Acid
Respiratory Mucosa
Smoking
Tretinoin
abstract
9-cis-RA treatment can restore RAR-beta expression in the bronchial epithelium of former smokers, raising the possibility that this retinoid has potential chemopreventive properties in former smokers.