Epithelial lesions in prophylactic mastectomy specimens from women with BRCA mutations Academic Article uri icon

Overview

MeSH Major

  • Breast
  • Genes, BRCA1
  • Mastectomy
  • Mutation

abstract

  • Lesions associated with an increased risk of subsequent malignancy are more common in PM specimens from women with BRCA mutations than in breast tissue obtained at autopsy from unaffected women without a known predisposition. This finding suggests that hereditary breast carcinoma has a preinvasive phase that may be detectable with aggressive surveillance.

publication date

  • April 2003

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1002/cncr.11225

PubMed ID

  • 12655515

Additional Document Info

start page

  • 1601

end page

  • 8

volume

  • 97

number

  • 7