The use of fresh frozen plasma after major hepatic resection for colorectal metastasis: Is there a standard for transfusion? Academic Article Article uri icon


MeSH Major

  • Bile Duct Neoplasms
  • Bile Ducts, Extrahepatic
  • Cholangiocarcinoma
  • Neoplasm Staging
  • Preoperative Care


  • There is no universal standard for FFP use following major hepatic resection for colorectal metastasis. Our criterion of a prothrombin time of 16-18 seconds is conservative but results only rarely in reoperation for bleeding. Prospective evaluation of a higher threshold for FFP administration, such as an International Normal Ratio of 2.0, should be performed to better define the guidelines for FFP use in patients undergoing major hepatectomy who have normal underlying hepatic parenchyma.

publication date

  • March 2003



  • Academic Article


Digital Object Identifier (DOI)

  • 10.1016/S1072-7515(02)01752-0

PubMed ID

  • 12648692

Additional Document Info

start page

  • 402

end page

  • 9


  • 196


  • 3