The use of fresh frozen plasma after major hepatic resection for colorectal metastasis: Is there a standard for transfusion?
Bile Duct Neoplasms
Bile Ducts, Extrahepatic
There is no universal standard for FFP use following major hepatic resection for colorectal metastasis. Our criterion of a prothrombin time of 16-18 seconds is conservative but results only rarely in reoperation for bleeding. Prospective evaluation of a higher threshold for FFP administration, such as an International Normal Ratio of 2.0, should be performed to better define the guidelines for FFP use in patients undergoing major hepatectomy who have normal underlying hepatic parenchyma.