Left ventricular mass regression in the LIFE study: Effect of previous antihypertensive treatment Academic Article Article uri icon


MeSH Major

  • Cardiovascular Diseases
  • Diabetes Mellitus, Type 2
  • Hypertrophy, Left Ventricular


  • Prior treatment is not associated with either greater LV mass or greater relative wall thickness when age, body mass index, sex, systolic BP, heart rate, or indices of LV volume load and systolic function are taken into account. In addition, prior treatment is not associated with lesser degrees of LV mass reduction. For design of future clinical trials, restriction of inclusion criteria to only previously untreated patients does not appear to be necessary when the selection criterion is electrocardiographically determined left ventricular hypertrophy.

publication date

  • March 2003



  • Academic Article


Digital Object Identifier (DOI)

  • 10.1016/S0895-7061(02)03258-2

PubMed ID

  • 12620695

Additional Document Info

start page

  • 180

end page

  • 6


  • 16


  • 3