Inhaled carbon monoxide suppresses the development of postoperative ileus in the murine small intestine Academic Article uri icon

Overview

MeSH Major

  • Abdomen
  • Carbon Monoxide
  • Intestinal Obstruction
  • Intestine, Small

abstract

  • These findings suggest that CO attenuates postoperative ileus by inhibiting selective elements within the inflammatory cascade and by enhanced induction of the anti-inflammatory cytokine IL-10. In addition, the early and enhanced induction of HO-1 potentially amplifies the anti-inflammatory effects of the HO-1 pathway by protection from free radical stress and by increasing the tissue availability of CO directly at the sites of inflammation.

publication date

  • February 2003

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1053/gast.2003.50060

PubMed ID

  • 12557144

Additional Document Info

start page

  • 377

end page

  • 91

volume

  • 124

number

  • 2