MR imaging findings in the contralateral breast of women with recently diagnosed breast cancer. Academic Article uri icon

Overview

MeSH

  • Aged
  • Biopsy, Needle
  • Female
  • Humans
  • Mammography
  • Middle Aged
  • Predictive Value of Tests
  • Retrospective Studies
  • Risk Factors

MeSH Major

  • Breast Neoplasms
  • Magnetic Resonance Imaging
  • Neoplasms, Multiple Primary

abstract

  • The purpose of this study was to determine the frequency and positive predictive value of biopsy performed on the basis of MR imaging findings in the contralateral breast in women with recently diagnosed breast cancer. We performed a retrospective review of records of 1336 consecutive breast MR imaging examinations over a 2-year period. Of these examinations, 223 imaged the asymptomatic, mammographically normal contralateral breast in women whose breast cancer was diagnosed within 6 months preceding MR imaging. Records of these 223 examinations were reviewed to determine the frequency of recommending contralateral breast biopsy and the biopsy results. Contralateral breast biopsy was recommended in 72 (32%) of 223 women and performed in 61 women. Cancer occult to mammography and physical examination was detected by MR imaging in 12 women, constituting 20% (12/61) of women who underwent contralateral biopsy and 5% (12/223) of women who underwent contralateral breast MR imaging. Among these 12 cancers, six (50%) were ductal carcinoma in situ (DCIS) and six (50%) were infiltrating carcinoma. The median size of infiltrating carcinoma was 0.5 cm (range, 0.1-1.0 cm). Contralateral biopsy revealed benign (n = 31) or high-risk (n = 18) lesions in 49 women, constituting 80% (49/61) of women who underwent contralateral biopsy and 22% (49/223) of women who underwent contralateral MR imaging. In women with recently diagnosed breast cancer, MR imaging of the contralateral breast led to a biopsy recommendation in 32%. Cancer was found in 20% of women who underwent contralateral breast biopsy and in 5% of women who underwent contralateral breast MR imaging.

publication date

  • February 2003

has subject area

  • Aged
  • Biopsy, Needle
  • Breast Neoplasms
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Mammography
  • Middle Aged
  • Neoplasms, Multiple Primary
  • Predictive Value of Tests
  • Retrospective Studies
  • Risk Factors

Research

keywords

  • Journal Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.2214/ajr.180.2.1800333

PubMed ID

  • 12540428

Additional Document Info

start page

  • 333

end page

  • 341

volume

  • 180

number

  • 2