Comprehension during informed consent in a less-developed country Academic Article Article uri icon


MeSH Major

  • Acquired Immunodeficiency Syndrome
  • Anti-Retroviral Agents


  • Few practical guidelines exist on how to ensure that research participants in less-developed countries understand the consent form before enrollment. In a study of HIV-1 transmission in Haiti, participants were required to pass an oral examination on the contents of the consent form with a passing score of 12/15 (80%) before enrollment. 15 individuals were given information during a single meeting with a physician, and three (20%) passed. 30 subsequent volunteers were given information by a counsellor during three meetings, and 24 (80%) passed. Formal assessment of research participants' comprehension of the consent form should be considered as a routine step in the informed consent process in less-developed countries.

publication date

  • October 26, 2002



  • Academic Article


Digital Object Identifier (DOI)

  • 10.1016/S0140-6736(02)11338-9

PubMed ID

  • 12414207

Additional Document Info

start page

  • 1301

end page

  • 2


  • 360


  • 9342