Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences Academic Article uri icon

Overview

MeSH Major

  • DNA, Complementary
  • Sequence Analysis, DNA

abstract

  • The National Institutes of Health Mammalian Gene Collection (MGC) Program is a multiinstitutional effort to identify and sequence a cDNA clone containing a complete ORF for each human and mouse gene. ESTs were generated from libraries enriched for full-length cDNAs and analyzed to identify candidate full-ORF clones, which then were sequenced to high accuracy. The MGC has currently sequenced and verified the full ORF for a nonredundant set of >9,000 human and >6,000 mouse genes. Candidate full-ORF clones for an additional 7,800 human and 3,500 mouse genes also have been identified. All MGC sequences and clones are available without restriction through public databases and clone distribution networks (see http:mgc.nci.nih.gov).

authors

publication date

  • December 24, 2002

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC139241

Digital Object Identifier (DOI)

  • 10.1073/pnas.242603899

PubMed ID

  • 12477932

Additional Document Info

start page

  • 16899

end page

  • 903

volume

  • 99

number

  • 26