Relationship between insulin resistance and an endogenous nitric oxide synthase inhibitor Academic Article uri icon

Overview

MeSH Major

  • Arginine
  • Hypoglycemic Agents
  • Metabolic Diseases
  • Metabolic Syndrome X
  • Nitric Oxide Synthase
  • Thiazoles
  • Thiazolidinediones
  • Vasodilator Agents

abstract

  • A significant relationship exists between insulin resistance and plasma concentrations of ADMA. Pharmacological intervention with rosiglitazone enhanced insulin sensitivity and reduced ADMA levels. Increases in plasma ADMA concentrations may contribute to the endothelial dysfunction observed in insulin-resistant patients.

publication date

  • March 20, 2002

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 11903029

Additional Document Info

start page

  • 1420

end page

  • 6

volume

  • 287

number

  • 11