In vivo imaging of proteolytic activity in atherosclerosis Academic Article Article uri icon

Overview

MeSH Major

  • Aortic Valve
  • Atherosclerosis
  • Calcinosis
  • Durapatite
  • Heart Valve Diseases
  • Muscle, Smooth, Vascular
  • Vascular Calcification

abstract

  • These studies indicate that cathepsin B, and potentially other proteases, may serve as a biomarker for vulnerable plaques when probed with beacons. The tomographic in vivo imaging method as well as catheter-based optical sensing methods could be readily adapted to screening and potentially to the molecular profiling of a number of proteases in vulnerable plaque in vivo.

publication date

  • June 11, 2002

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1161/01.CIR.0000017860.20619.23

PubMed ID

  • 12057992

Additional Document Info

start page

  • 2766

end page

  • 71

volume

  • 105

number

  • 23