Vascular structural and functional changes in type 2 diabetes mellitus: Evidence for the roles of abnormal myogenic responsiveness and dyslipidemia Academic Article Article uri icon

Overview

MeSH Major

  • Cornea
  • Diabetes Mellitus, Type 1
  • Diabetes Mellitus, Type 2
  • Diabetic Neuropathies
  • Microscopy, Confocal

abstract

  • These results demonstrate vascular hypertrophy in small arteries from patients with type 2D. This could be a consequence of impaired myogenic responsiveness, which will increase wall stress for a given intraluminal pressure, which may be a stimulus for vascular hypertrophy. A substantial proportion of endothelial dysfunction can be attributed to an effect of the abnormal lipid profile seen in such patients.

publication date

  • December 10, 2002

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1161/01.CIR.0000041432.80615.A5

PubMed ID

  • 12473548

Additional Document Info

start page

  • 3037

end page

  • 43

volume

  • 106

number

  • 24