Dual vs single protease inhibitor therapy following antiretroviral treatment failure: A randomized trial
HIV Protease Inhibitors
Reverse Transcriptase Inhibitors
In this study of antiretroviral-experienced patients with advanced immunodeficiency, viral load suppression to below 200 copies/mL was achieved in 31% of patients with regimens containing 4 or 5 new drugs. Use of 2 PIs, being naive to NNRTIs, and baseline hypersusceptibility to efavirenz were associated with a favorable outcome.