Concomitant leflunomide therapy in patients with active rheumatoid arthritis despite stable doses of methotrexate: A randomized, double-blind, placebo-controlled trial Academic Article uri icon

Overview

MeSH Major

  • Anti-Inflammatory Agents, Non-Steroidal
  • Antimetabolites
  • Arthritis, Rheumatoid
  • Isoxazoles
  • Methotrexate

abstract

  • Combination therapy with leflunomide and methotrexate provides statistically significant clinical benefit in patients with active rheumatoid arthritis who are receiving methotrexate therapy. Leflunomide plus methotrexate is generally well tolerated and can be used safely with appropriate liver enzyme and hematologic monitoring.

publication date

  • November 5, 2002

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 12416946

Additional Document Info

start page

  • 726

end page

  • 33

volume

  • 137

number

  • 9