Craniotomy for central nervous system metastases in epithelial ovarian carcinoma
Drug Screening Assays, Antitumor
Molecular Targeted Therapy
Randomized Controlled Trials as Topic
Despite optimal cytoreduction, platinum-based chemotherapy, and negative second-look surgical assessment, patients with ovarian cancer can fail distantly with CNS metastases. Craniotomy with adjuvant radiation therapy can provide control of brain metastases in the majority of these patients and may result in improved survival over radiation therapy alone in selected patients.